Cimetidine tagamet ; digoxin digitalis, lanoxin ; levothyroxine synthroid ; phenytoin dilantin ; quinidine quin-g ; ranitidine zantac ; tetracycline ala-tet, brodspec, panmycin, sumycin, tetracap ; theophylline elixophyllin, theo-24, theochron, uniphyl, and others ; a blood thinner such as warfarin coumadin, jantoven ; or certain antibiotics such as ciprofloxacin cipro , levofloxacin levaquin , lomefloxacin maxaquin , ketoconazole nizoral , and others.
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penicillin g benzathine; penicillin g procaine minor displacement of penicillins from plasma protein binding sites by highly protein bound drugs like digoxin will elevate the level of free penicillin in the serum.
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in deciding whether a patient s symptoms are due to digoxin, the clinical state together with the serum potassium level and thyroid function are important factors see section 4.
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eplerenone inspra ; digoxin digitalis, lanoxin ; candesartan atacand , losartan cozaar, hyzaar , valsartan diovan , or telmisartan micardis ; glycopyrrolate robinul ; mepenzolate cantil ; quinidine quinaglute, quinidex, quin-release ; atropine donnatal, and others , benztropine cogentin , dimenhydrinate dramamine , methscopolamine pamine , or scopolamine transderm-scop ; a bronchodilator such as ipratroprium atrovent or tiotropium spiriva ; bladder or urinary medications such as darifenacin enablex , flavoxate urispas , oxybutynin ditropan, oxytrol , tolterodine detrol , or solifenacin vesicare ; irritable bowel medications such as dicyclomine bentyl , hyoscyamine anaspaz, cystospaz, levsin, and others , or propantheline pro-banthine ; an ace inhibitor such as benazepril lotensin , captopril capoten , fosinopril monopril , enalapril vasotec , lisinopril prinivil, zestril , moexipril univasc , perindopril aceon , quinapril accupril , ramipril altace , or trandolapril mavik ; or any type of diuretic water pill such as bumetanide bumex , chlorothiazide diuril , chlorthalidone hygroton, thalitone , ethacrynic acid edecrin , furosemide lasix , hydrochlorothiazide hctz, hydrodiuril, hyzaar, lopressor, vasoretic, zestoretic , indapamide lozol , metolazone mykrox, zarxolyn , or torsemide demadex .
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dosage calculation parallels that for digoxin tablets and the same caveats apply to intravenous use of digoxin as for the oral preparation.
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because of the significant tissue binding of digoxin it is not removed by dialysis, plasma exchange or exchange transfusions, or during cardiopulmonary bypass.
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Digoxin is used to treat certain heart problems such as some arrhythmias called atrial fibrillation and atrial flutter and heart failure.
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