The following principles phenomena apply gradual discontinuation of offending agent taper if key treatment principles opioid- or barbiturate-containing aggressive treatment of resulting severe headache diagnosing the specific primary headache entity hydration, including intravenous fluids and support determining attack frequency and severity in severe cases treat nausea, etc establishing the presence or absence of comorbid ill- the development of pharmacologic prophylaxis nesses psychiatric, neurological, medical, etc implementation of behavioral therapies identifying confounding factors, including external or use of infusion or hospitalization techniques for internal phenomena, such as advanced and severe conditions rebound rebound or medication overuse headaches, which psychologic, comorbid illnesses and medication most likely result from chronic changes to receptors, factors ie, estrogen replacement, nitroglycerine must be distinguished from headaches resulting from hormonal disturbances exposure to toxic substances or other agents or drugs.
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