During the intensive phase of standard treatment, patients take a daily combination of four medications isoniazid, rifampicin, pyrazinamide and ethambutol.
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caffeine moderate although isoniazid does not inhibit mitochondrial mao, it does appear to inhibit plasma mao.
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nilotinib major avoid the concomitant use of nilotinib, a cyp3a4 substrate, isoniazid, inh, a strong cyp3a4 inhibitor; nilotinib levels may increase.
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