Promethazine hydrochloride and codeine phosphate syrup is indicated for the temporary relief of coughs and urs associated with allergy or the common cold.
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promethazine is metabolized by the liver to a variety of compounds; the sulfoxides of promethazine and n-demethylpromethazine are the predominant metabolites appearing in the urine.
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it is recommended that the lowest effective dose of promethazine hydrochloride be used in pediatric patients 2 years of age and older and concomitant administration of other drugs with respiratory depressant effects be avoided.
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promethazine with codeine oral solution should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.
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