Nitrofurantoin derivative of nitrofuran used as an antibacterial medicine trade name macrodantin effective against a broad range of gram-positive and gram-negative bacteria; used to treat infections of the urinary tract.
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the following laboratory adverse events also have been reported with the use of nitrofurantoin glucose-6- phosphate dehydrogenase deficiency anemia see warnings , agranulocytosis, leukopenia, granulocytopenia, hemolytic anemia, thrombocytopenia, megaloblastic anemia.
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patients should be advised to take nitrofurantoin oral suspension with food to further enhance tolerance and improve drug absorption.
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all the strains were resistant to nalidixic acid, tobramycin, gentamicin, chloramphenicol, tetracycline and nitrofurantoin.
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