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Indomethacin or phenylpropanolamine because they may decrease betapace s effectiveness clonidine, diltiazem, mibefradil, nifedipine, or verapamil because the risk of side effects, such as low blood pressure or heart problems, may be increased amiodarone, antiarrhythmics eg, quinidine, propafenone , arsenic, cisapride , dofetilide, droperidol, h 1 antagonists eg, astemizole, terfenadine , ketanserin, macrolides and ketolides eg, erythromycin, azithromycin , mefloquine, phosphodiesterase type 5 inhibitors eg, sildenafil , phenothiazines eg, thioridazine , quinolones eg, ciprofloxacin , or ziprasidone because the risk of abnormal heart rhythms may be increased bupivacaine, cocaine, epinephrine, insulin, lidocaine, meglitinide antidiabetics eg, nateglinide , nifedipine, or quinazolines eg, prazosin because the risk of their side effects may be increased by betapace certain stimulants eg, albuterol, pseudoephedrine , phenformin, or theophyllines eg, aminophylline because their effectiveness may be decreased by betapace.

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