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The efficacy and safety of risperdal in the treatment of irritability associated with autistic disorder were established in two 8-week, double-blind, placebo-controlled trials in 156 children and adolescent patients, aged 5 to 16 years see indications and usage , adverse reactions and clinical studies .
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Clarithromycin, cyclosporine, estrogens eg, estradiol , oral contraceptives eg, birth control pills , or ketoconazole because they may increase the risk of prednisolone s side effects barbiturates eg, phenobarbital , carbamazepine, ephedrine, hydantoins eg, phenytoin , or rifampin because they may decrease prednisolone s effectiveness anticholinesterases eg, pyridostigmine , aspirin, diuretics eg, hydrochlorothiazide, furosemide , methotrexate, mifepristone, quinolone antibiotics eg, ciprofloxacin , ritodrine, or live or attenuated live vaccines because the risk of their side effects may be increased by prednisolone anticoagulants eg, warfarin , hydantoins eg, phenytoin , or killed or inactivated vaccines because their effectiveness may be decreased by prednisolone.
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